Interacting Drugs |
Bisoprolol and hydrochlorothiazide vs Dronedarone |
Security Level |
|
Mechanism |
Dronedarone: May enhance the bradycardic effect of Beta-Blockers. Dronedarone may increase the serum concentration of Beta-Blockers. This likely applies only to those agents that are metabolized by CYP2D6. |
Management |
Use lower initial beta-blocker doses; adequate tolerance of the combination, based on ECG findings, should be confirmed prior to any increase in beta-blocker dose. |
Bisoprolol and hydrochlorothiazide vs Dronedarone
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Other Interactions of Bisoprolol and hydrochlorothiazide
Other Interactions of Dronedarone
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