Bacitracin, neomycin, polymyxin B, and hydrocortisone vs Penicillins

Interacting Drugs
Bacitracin, neomycin, polymyxin B, and hydrocortisone
vs
Penicillins
Security Level
Moderate, Consider therapy modification
Mechanism
Penicillins: May decrease the serum concentration of Aminoglycosides. Primarily associated with extended spectrum penicillins, and patients with renal dysfunction. Exceptions: Amoxicillin; Ampicillin; Cloxacillin; Dicloxacillin; Nafcillin; Oxacillin; Penicillin G (Parenteral/Aqueous); Penicillin G Benzathine; Penicillin G Procaine; Penicillin V Potassium.
Management
Consider therapy modification

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