Ampicillin and sulbactam vs Chloroquine

Interacting Drugs
Ampicillin and sulbactam
vs
Chloroquine
Security Level
Moderate, Consider therapy modification
Mechanism
Chloroquine: May decrease the serum concentration of Ampicillin.
Management
Choroquine prescribing information recommends separating administration of ampicillin and chloroquine by at least 2 hours to minimize any potential negative impact of chloroquine on ampicillin bioavailability.

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