Amobarbital vs Calcium Channel Blockers

Interacting Drugs
Amobarbital
vs
Calcium Channel Blockers
Security Level
Minor, Monitor Therapy
Mechanism
Calcium Channel Blockers: Barbiturates may increase the metabolism of Calcium Channel Blockers.
Management
Monitor for decreased therapeutic effects of calcium channel blockers with concomitant barbiturate therapy. Calcium channel blocker dose adjustments may be necessary. Nimodipine Canadian labeling contraindicates concomitant use with phenobarbital. Exceptions: Clevidipine.

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