Amlodipine vs Rifamycin Derivatives

Interacting Drugs
Amlodipine
vs
Rifamycin Derivatives
Security Level
Moderate, Consider therapy modification
Mechanism
Rifamycin Derivatives: May increase the metabolism of Calcium Channel Blockers. This primarily affects oral forms of calcium channel blockers.
Management
The labeling for some U.S. and Canadian calcium channel blockers contraindicate use with rifampin however recommendations vary. Consult appropriate labeling.

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