Amlodipine, olmesartan, and hydrochlorothiazide vs Phenytoin

Interacting Drugs
Amlodipine, olmesartan, and hydrochlorothiazide
vs
Phenytoin
Security Level
Moderate, Consider therapy modification
Mechanism
Phenytoin: Calcium Channel Blockers may increase the serum concentration of Phenytoin.
Management
Monitor for phenytoin toxicity with concomitant use of a calcium channel blocker (CCB) or decreased phenytoin effects with CCB discontinuation. Monitor for decreased CCB therapeutic effects. Nimodipine Canadian labeling contraindicates use with phenytoin.

Subscribe for latest updates

Subscribe to our e-mail newsletter to receive updates.

No comments yet.

Post Review about Amlodipine, olmesartan, and hydrochlorothiazide vs Phenytoin