Aliskiren and amlodipine vs Simvastatin

Interacting Drugs
Aliskiren and amlodipine
vs
Simvastatin
Security Level
Moderate, Consider therapy modification
Mechanism
Simvastatin: AmLODIPine may increase the serum concentration of Simvastatin.
Management
Avoid the concurrent use of amlodipine with simvastatin when possible. If used together, avoid doses of simvastatin greater than 20 mg/day (for adults).

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