Acenocoumarol vs Drotrecogin Alfa

Interacting Drugs
Acenocoumarol
vs
Drotrecogin Alfa
Security Level
Moderate, Consider therapy modification
Mechanism
Drotrecogin Alfa: Vitamin K Antagonists may enhance the adverse/toxic effect of Drotrecogin Alfa. Bleeding may occur.
Management
Weigh potential benefits of drotrecogin against increased bleeding risk in patients who have received oral anticoagulants within 1 week or have INR 3 or greater. Monitor for bleeding and immediately stop infusion if clinically important bleeding occurs.

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Other Interactions of Acenocoumarol

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Other Interactions of Drotrecogin Alfa

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