Sulphathiazole

Indications	Vaginal Vaginal infections *Adult:* Cream (Sulphathiazole 34.2 mg/g, sulphacetamide 28.6 mg/g, sulphabenzamide 37 mg/g and urea 6.4 mg/g): 5g is applied intra-vaginally bid for 4 to 6 days. Thereafter the dosage may be reduced to one-half or one-quarter. *Renal impairment:*
Contraindications	Sulphonamide sensitivity, kidney disease, glucose 6-phosphate deficiency (G6PD).
Mechanism of Actions	Sulfathiazole interferes with nucleic acid synthesis in microorganisms by blocking the conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid.It has properties similar to sulfamethoxazole. It is a short-acting sulfonamide, now rarely used systemically due to its toxicity.
ATC Classification	D06BA02 - sulfathiazole ; Belongs to the class of topical sulfonamides used in the treatment of dermatological diseases. J01EB07 - sulfathiazole ; Belongs to the class of short-acting sulfonamides. Used in the systemic treatment of infections.
Available As	Sulphathiazole 3.42%

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Sulphathiazole is used in following diseases

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