Sucralfate

Indications
Oral
Chronic gastritis
Adult: 1 g 4 times daily or 2 g bid for 4-8 wk, may extend up to 12 wk if necessary. Maintenance dose of 1 g bid may be given to prevent the recurrence of duodenal ulcers. Max: 8 g daily.
Child: 1 mth-2 yr: 250 mg 4-6 times daily; 2-12 yr: 500 mg 4-6 times daily and 12-18 yr: 1 g 4-6 times daily.
Oral
Peptic ulcer
Adult: 1 g 4 times daily or 2 g bid for 4-8 wk, may extend up to 12 wk if necessary. Maintenance dose of 1 g bid may be given to prevent the recurrence of duodenal ulcers. Max: 8 g daily.
Child: 1 mth-2 yr: 250 mg 4-6 times daily; 2-12 yr: 500 mg 4-6 times daily and 12-18 yr: 1 g 4-6 times daily.
Oral
Prophylaxis of gastrointestinal haemorrhage from stress ulceration
Adult: 1 g 6 times daily. Not to exceed 8 g daily.
Child: 1 mth-2 yr: 250 mg 4-6 times daily; 2-12 yr: 500 mg 4-6 times daily and 12-18 yr: 1 g 4-6 times daily.
Warnings / Precautions
Systemic aluminum toxicity may occur in patients with chronic renal failure. Neonates, children; pregnancy and lactation.
Adverse Reactions
Constipation, diarrhoea, nausea, dizziness, dry mouth. GI disturbances, rash, pruritus, headache, vertigo, back pain, drowsiness.
Overdose Reactions
Sucralfate is poorly absorbed from the GI tract thus the risk from overdosage is minimal.
Drug Interactions
Avoid antacids within 30 min of sucralfate admin. May reduce absorption of tetracyclines, ranitidine, ketoconazole, theophylline, phenytoin, cimetidine and digoxin (ensure a dosing interval of at least 2 hr between admin of sucralfate and other non-antacid medications).
See Below for More sucralfate Drug Interactions
Mechanism of Actions
Sucralfate protects GI lining against peptic acid, pepsin and bile salts by binding with positively-charged proteins in exudates forming a viscous paste-like adhesive substance thus forming a protective coating.
Onset: 1-2 hr.
Duration: 6 hr.
Absorption: <5% after oral admin.
Distribution: Acts locally at ulcer sites; unbound in GI tract to aluminum and sucrose sulfate.
Excretion: Mainly in the urine.
Administration
Should be taken on an empty stomach. (Take on an empty stomach 1 hr before or 2 hr after meals.)
Storage Conditions
Oral: Store at 20-25°C.
ATC Classification
A02BX02 - sucralfate ; Belongs to the class of other drugs used in the treatment of peptic ulcer and gastro-oesophageal reflux disease (GERD).
Storage
Oral: Store at 20-25°C.
Available As
  • Sucralfate 1 gm
  • Sucralfate 1 mg
  • Sucralfate 100 mg
  • Sucralfate 1000 mg
  • Sucralfate 2 gm
  • Sucralfate 500 mg
  • Sucralfate 7%
  • Sucralfate 7% w/w
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    Sucralfate Containing Brands

    Click on Prescription information to see Indications ( Uses ), Contraindications, Prescription information of respective Constituents.

    Brand Name Manufacturer Unit/Price Package unit/Price Constituents/Unit
    Syrup Crasia O (200 ml) Eucrasia (Alpic Biotech Ltd.) 5 ml
    ₹ 2.48
    200 ml
    ₹ 99.00
  • More Information Sucralfate 1 gm
  • More Information Oxethazine 20 mg
  • See Brands having above combination
    Syrup Esafte O (100 ml) Allenge India 1 ml
    ₹ 0.71
    100 ml
    ₹ 70.50
  • More Information Oxethazine 10 mg
  • More Information Sucralfate 1 gm
  • See Brands having above combination
    Suspension Erocot O (100 ml) Nodysis Pharma Pvt. Ltd. 5 ml
    ₹ 2.60
    100 ml
    ₹ 51.92
  • More Information Oxetacaine 20 mg
  • More Information Sucralfate 1 gm
  • See Brands having above combination
    Suspension Lorcus O (200 ml) Ester Formulations 5 ml
    ₹ 2.83
    200 ml
    ₹ 113.00
  • More Information Sucralfate 1 gm
  • More Information Oxethazine 20 mg
  • See Brands having above combination
    Tablet Mucogard (1000 mg) Themis Pharmaceuticals Limited 1 Tablet
    ₹ 1.31
    10 Tablet
    ₹ 13.07
  • More Information Sucralfate 1000 mg
  • See Brands having above combination
    Tablet Recolfate (1000 mg) Reckitt & Benckiser (India) Ltd. 1 Tablet
    ₹ 1.50
    4 Tablet
    ₹ 6.00
  • More Information Sucralfate 1000 mg
  • See Brands having above combination
    Syrup Samsuc (100 ml) Aamorb Pharmaceuticals Pvt Ltd 5 ml
    ₹ 2.98
    100 ml
    ₹ 59.50
  • More Information Sucralfate 1 gm
  • More Information Oxethazine 20 mg
  • See Brands having above combination
    Syrup Starlix (100 ml) Scoshia Remedy Inc. 5 ml
    ₹ 2.80
    100 ml
    ₹ 56.00
  • More Information Sucralfate 1 gm
  • See Brands having above combination
    Suspension Sucramax OT (100 ml) Hamax Pharmaceuticals 1 ml
    ₹ 0.75
    100 ml
    ₹ 74.88
  • More Information Sucralfate 1 gm
  • More Information Oxethazine 20 mg
  • See Brands having above combination
    Tablet Ulcerfate (1000 mg) Sun Pharmaceutical Industries Ltd. 1 Tablet
    ₹ 1.97
    6 Tablet
    ₹ 11.81
  • More Information Sucralfate 1000 mg
  • See Brands having above combination
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    Sucralfate is used in following diseases

    We are Developing Our database, More results coming soon.

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    Drug - Drug Interactions of Sucralfate
    Interaction
    Moderate, Consider therapy modification Doxycycline vs Sucralfate
    Moderate, Consider therapy modification Acenocoumarol vs Sucralfate
    Moderate, Consider therapy modification Sodium phosphate vs Sucralfate
    Major, Avoid combination Paricalcitol vs Sucralfate
    Moderate, Consider therapy modification Eltrombopag vs Sucralfate
    Moderate, Consider therapy modification Quinidine vs Sucralfate
    Moderate, Consider therapy modification Norfloxacin vs Sucralfate
    Moderate, Consider therapy modification Digoxin vs Sucralfate
    Moderate, Consider therapy modification Demeclocycline vs Sucralfate
    Major, Avoid combination Vitamin D2 (ergocalciferol) vs Sucralfate
    Pages: 1 2 3 4 5 Next