Indications |
Oral Food allergy Adult: 200 mg four times daily. May double the dose if effect is not satisfactory within 2-3 wk. Child: 100 mg four times daily. May double the dose if effect is not satisfactory within 2-3 weeks. Max Dosage: 40 mg/kg/day. Renal impairment: Dosage adjustment may be needed. Hepatic impairment: Dosage adjustment may be needed. Oral Mastocytosis Adult: 200 mg four times daily. May double the dose if effect is not satisfactory within 2-3 wk. Child: 100 mg four times daily. May double the dose if effect is not satisfactory within 2-3 weeks. Max Dosage: 40 mg/kg/day. Renal impairment: Dosage adjustment may be needed. Hepatic impairment: Dosage adjustment may be needed. Nasal Allergic rhinitis Adult: 2.5 or 5 mg of a 2% or 4% soln is admin as drops or spray into each nostril 4 times daily. Renal impairment: Dosage adjustment may be needed. Hepatic impairment: Dosage adjustment may be needed. Inhalation Asthma prophylaxis Adult: 20 mg four times daily as dry powder/nebulised soln or 10 mg four times daily as aerosol, increased to 6-8 times daily if necessary, reduced to 5 mg four times daily once asthma has been stabilised. Additional doses may be taken before exercise. Elderly: Renal impairment: Dosage adjustment may be needed. Hepatic impairment: Dosage adjustment may be needed. Ophthalmic Allergic conjunctivitis Adult: Instill 2 drops of a 4% soln 4-6 times daily or apply a 4% oint bid-tid. Elderly: Renal impairment: Dosage adjustment may be needed. Hepatic impairment: Dosage adjustment may be needed. |
Contraindications |
Hypersensitivity. |
Warnings / Precautions |
Lactation, cardiac arrhythmias, hepatic or renal dysfunction. |
Adverse Reactions |
Nausea, headache, dizziness, unpleasant taste, joint pain and swelling, skin rashes, aggravation of asthma, pulmonary infiltrates with eosinophilia, urticaria. Bronchospasm, wheezing, cough, nasal congestion and throat irritation following inhalation of dry powder. Intranasal use: Transient irritation of nasal mucosa. Sneezing and epistaxis (occasional). Eye drops: Transient burning and stinging. |
Mechanism of Actions |
Cromoglycic acid inhibits degranulation of mast cells and therefore suppresses the release of histamine, leukotrienes and slow-reacting substance of anaphylaxis. Absorption: Oral: Poorly absorbed from the GIT with only 1% bioavailability. Inhalation: 8-10% of a dose of fine powd is deposited and rapidly absorbed from the lungs. Intranasal: < 7% of the dose is absorbed. Ophthalmic: 0.03% is absorbed. |
Storage Conditions |
Inhalation: Store at 25°C. Nasal: Store at 25°C. Ophthalmic: Store at 25°C. Oral: Store at 25°C. |
ATC Classification |
A07EB01 - cromoglicic acid ; Belongs to the class of antiallergic antiinflammatory, excluding corticosteroids. Used in the treatment of intestinal inflammation. R01AC01 - cromoglicic acid ; Belongs to the class of topical antiallergic preparations, excluding corticosteroids. Used as antiallergic agents. R03BC01 - cromoglicic acid ; Belongs to the class of other inhalants used in the treatment of obstructive airway diseases, antiallergic agents. S01GX01 - cromoglicic acid ; Belongs to the class of other ophthalmologic antiallergics. D11AX17 - 色甘酸 ; |
Storage |
Inhalation: Store at 25°C. Nasal: Store at 25°C. Ophthalmic: Store at 25°C. Oral: Store at 25°C. |
Available As |
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Sodium Cromoglycate
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Post Review about Sodium Cromoglycate
Sodium Cromoglycate Containing Brands
to see Indications ( Uses ), Contraindications, Prescription information of respective Constituents.
Benzalkonium Chloride 0.01% w/vSodium Cromoglycate is used in following diseases
Drug - Drug Interactions of Sodium Cromoglycate
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