S Atenolol

Indications
 Oral
Angina pectoris
Adult: 50-100 mg once daily.
Renal impairment: Dosage adjustments may be required.
Oral
Hypertension
Adult: 50-100 mg once daily.
Renal impairment: Dosage adjustments may be required.
Oral
Prophylaxis of migraine
Adult: 50-100 mg daily.
Renal impairment: Dosage adjustments may be required.
Contraindications
 Hypersensitivity, 2nd and 3rd degree heart block, cardiogenic shock, bronchospasm, history of obstructive airway disease, metabolic acidosis, hypotension, severe peripheral arterial disease, sinus bradycardia.
Warnings / Precautions
 Renal failure, DM, children, pregnancy and lactation. May mask symptoms of hyperthyroidism and hypoglycaemia. Avoid abrupt withdrawal.
Adverse Reactions
 Fatigue, cold extremities, bradycardia, heart failure, headache, dizziness, hallucinations, confusion and sleep disturbances.
Overdose Reactions
 May cause severe and fatal CV depression. Activated charcoal or gastric lavage may be considered if patient presents within 1 hr of ingestion.
Drug Interactions
 Disopyramide when given in combination with atenolol depresses myocardial contractility and may precipitate cardiac failure. Efficacy may be antagonised by NSAIDs.
Potentially Fatal: Concurrent use with verapamil may precipitate heart failure in patients with impaired left ventricular function. Simultaneous withdrawal of atenolol and clonidine may result in severe rebound hypertension.
See Below for More s-atenolol Drug Interactions
Mechanism of Actions
 S-Atenolol selectively blocks the β1 receptors, and it significantly reduces both maximal and submaximal exercise heart rates in a dose-related manner. Endocrine and metabolic actions of S-atenolol include lowering of plasma renin activity and free fatty acids.
ATC Classification
 C07AB11 - s-atenolol ; Belongs to the class of selective beta-blocking agents. Used in the treatment of cardiovascular diseases.
Available As
  • S Atenolol 12.5 mg
  • S Atenolol 25 mg
  • S Atenolol 50 mg

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