Racecadotril

Indications
Oral
Acute diarrhoea
Adult: 100 mg tid, up to 7 days.
Warnings / Precautions
Renal insufficiency, pregnancy, lactation.
Adverse Reactions
Vomiting, nausea, constipation, abdominal pain, thirst, vertigo and headache.
Mechanism of Actions
Racecadotril increases the availability of endogenous opioids (enkephalins) by inhibiting the membrane-bound enkephalinase. These enkephalins activate δ-opioid receptors in the GI tract. This leads to a reduction in cAMP mucosal levels, resulting in a reducted secretion of water and electrolytes in the intestinal lumen.
Onset: Within 30 min.
Administration
May be taken with or without food.
ATC Classification
A07XA04 - racecadotril ; Belongs to the class of other antidiarrheals.
Available As
  • Racecadotril 1 gm
  • Racecadotril 10 mg
  • Racecadotril 100 mg
  • Racecadotril 15 mg
  • Racecadotril 3 gm
  • Racecadotril 30 mg
  • Racecadotril 50 mg
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