Indications |
Oral Benign prostatic hyperplasia Adult: 5 mg once daily for ≥6 mth, if necessary. Oral Male pattern baldness Adult: 1 mg once daily. |
Contraindications |
Children, exposure of pregnant women to finasteride either via direct contact with crushed tab or through semen of male sexual partners who are taking finasteride; pregnancy, lactation. |
Warnings / Precautions |
Undiagnosed prostate cancer, liver dysfunction, obstructive uropathy. |
Adverse Reactions |
Gynaecomastia, decreased libido, impotence, reduction in the volume of ejaculate, testicular pain. Hypersensitivity reactions e.g. swelling of lips and face, urticaria, rashes. |
Lab Interactions |
May mask serum markers (PSA) for prostate cancer. |
Food Interactions |
Food may delay the rate and reduce the extent of oral absorption |
Mechanism of Actions |
Finasteride is a competitive inhibitor of the enzyme 5-α reductase which converts testosterone to dihydrotestosterone (DHT), thus resulting in decreased serum levels of DHT. Absorption: Absorbed from the GI tract (oral); peak plasma concentrations after 1-2 hr. Distribution: Protein-binding: 90%. Metabolism: Hepatic. Excretion: Urine and faeces (as metabolites); <60 yr: 6 hr; >70 yr: 8 hr (elimination half-life). |
Administration |
May be taken with or without food. |
Storage Conditions |
Oral: Store at 15-30°C. |
ATC Classification |
D11AX10 - finasteride ; Belongs to the class of other dermatologicals. G04CB01 - finasteride ; Belongs to the class of testosterone-5-alpha reductase inhibitors. Used in the treatment of benign prostatic hypertrophy. |
Storage |
Oral: Store at 15-30°C. |
Available As |
|
Finasteride
Post Review about Finasteride Click here to cancel reply.
Finasteride Containing Brands
Finasteride is used in following diseases
Drug - Drug Interactions of Finasteride
Latest News
- FDA approves Ruconest for treatment of hereditary angioedema
- FDA recommend against aspirin to prevent First Heart Attacks
- FDA approves Pomalyst (pomalidomide) for advanced multiple myeloma
- FDA approves three new drug treatments for type 2 diabetes
- Long-term consequences of vaginal delivery on the pelvic floor
No comments yet.