Indications |
Oral Gastrointestinal tract spasm Adult: 10-20 mg tid. Child: 2-12 yr: 10 mg tid; 6 mth-2 yr: 5-10 mg 3-4 times daily. Elderly: Intramuscular Gastrointestinal tract spasm Adult: 20 mg 4 times a day given only for 1-2 days. Replace with oral therapy as soon as possible. |
Contraindications |
Intestinal obstruction; intestinal atony; myasthenia gravis; glaucoma; reflux oesophagitis; infants <6 mth; lactation. |
Warnings / Precautions |
Hepatic or renal disease, urinary retention, paralytic ileus, hyperthyroidism, hypertension, congestive heart failure, cardiac tachyarrhythmia, children, elderly, pregnancy. |
Adverse Reactions |
Difficulty in accommodation, exacerbation of glaucoma; tachycardia, palpitations, arrhythmias; urinary retention; restlessness; confusion, excitement, hallucination and delirium. Potentially Fatal: Respiratory arrest in infants <10 wk. |
Overdose Reactions |
Symptoms: headache, dizziness, nausea, dry mouth, difficulty in swallowing, dilated pupils and hot dry skin. Management: treatment is symptomatic. Reduce drug absorption by emetics or gastric lavage. |
Drug Interactions |
Antagonise the effect of drugs that affect GI motility e.g. metoclopramide. Absorption affected by concurrent admin with antacids. See Below for More dicycloverine hydrochloride Drug Interactions |
Mechanism of Actions |
Dicycloverine HCl relieves smooth muscle spasm in the GI and urinary tract. This effect is partly due to antimuscarinic action and partly direct action on the smooth muscle. |
Administration |
Dicycloverine: May be taken with or without food. (May be taken before or after meals.) |
Storage Conditions |
Intramuscular: Store below 30°C. Oral: Store below 30°C. |
ATC Classification |
A03AA07 - dicycloverine ; Belongs to the class of synthetic anticholinergics, esters with tertiary amino group. Used in the treatment of functional bowel disorders. |
Storage |
Intramuscular: Store below 30°C. Oral: Store below 30°C. |
Available As |
|
Dicyclomine (Dicycloverine)
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Dicyclomine (Dicycloverine) Containing Brands
Dicyclomine (Dicycloverine) is used in following diseases
Drug - Drug Interactions of Dicyclomine (Dicycloverine)
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