Copper

Indications
Oral
Nutritional deficiency
Adult: As elemental copper. 900 mcg/day (max: 10 mg/day). Pregnant females 1 mg/day. Lactating females 1.3 mg/day. Adolescents ≥14 yr 890 mcg/day (max: 8 mg/day) .
Child: Birth-6 mth 200 mcg/day. 7-12 mth 220 mcg/day. 1-3 yr 340 mcg/day (max: 1 mg/day). 4-8 yr 440 mcg/day (max: 3 mg/day). 9-13 yr 700 mcg/day (max: 5 mg/day).
Intravenous
Nutritional deficiency
Adult: TPN 0.5-1.5 mg/day of elemental copper.
Child: TPN Full-term infants & childn 20 mcg elemental copper/kg/day IV. May be added to TPN.
Intravenous
Copper deficiency
Adult: 3 mg/day of elemental copper. May be added to TPN.
Child: Full-term infants & childn 20-30 mcg/kg/day IV of elemental copper. May be added to TPN.

Special Populations: Hepatic impairment: copper may accumulate if biliary obstruction or hepatic disease is present.
Warnings / Precautions
Young children. Pregnancy, lactation. Wilson's disease. Chronic liver/renal failure. Hepatic impairment: copper may accumulate if biliary obstruction or hepatic disease is present.
Adverse Reactions
Excessive dose may cause abdominal pain or cramps, diarrhoea, nausea/vomiting & metallic taste.
Overdose Reactions
Severe GI effects. In extreme or long term overdosage, symptoms may be similar to that of Wilson's disease. Treatment is symptomatic and may involve the use of a chelating agent (e.g. penicillamine, trientine and zinc) to remove any absorbed metal. Dialysis may be useful.
Drug Interactions
Ascorbic acid (large doses). Inhibit intestinal absorption by oral iron supplements, oral/parenteral Zn, D-Penicillamine or trientine chelate copper. Excessive amounts of molybdenum may produce copper deficiency.
See Below for More copper sulfate Drug Interactions
Food Interactions
Concomitant intake with foods rich in phytic acid (unleavened bread, raw beans, seeds, nuts & grains & soy isolates) may decrease absorption of copper. Diets high in fructose may decrease copper status.
Mechanism of Actions
An essential trace element important for proper functioning of many metalloenzymes including ceruloplasmin, ferroxidase II, lysyl oxidase, monoamine oxidase, Zn-copper superoxide dismutase, tyrosinase, dopamine-β-hydroxylase & cytochrome-c-oxidase. It is involved in erythropoiesis & leukopoiesis, bone mineralisation, elastin & collagen cross-linking, oxidative phosphorylation, catecholamine metabolism, melanin formation & antioxidant protection of cells. May also play a role in iron turnover, ascorbic acid metabolism, phospholipid metabolism, myelin formation, glucose homeostasis & cellular immune defense.
Absorption: Principally absorbed in the small intestine.
Excretion: 80% eliminated via the bile. Little excretion by the kidney.
ATC Classification
V03AB20 - copper sulfate ; Belongs to the class of antidotes. Used in the management of phosphorus poisoning.
Available As
  • Copper –
  • Copper 0.01 mg
  • Copper 0.04 mg
  • Copper 0.05 mg
  • Copper 0.06 mg
  • Copper 0.1 mg
  • Copper 0.105 mg
  • Copper 0.11 mg
  • Copper 0.15 mg
  • Copper 0.2 mg
  • Copper 0.22 mg
  • Copper 0.25 mg
  • Copper 0.3 mg
  • Copper 0.35 mg
  • Copper 0.4 mg
  • Copper 0.45 mg
  • Copper 0.47 mg
  • Copper 0.5 mg
  • Copper 0.54 mg
  • Copper 0.6 mg
  • Copper 0.65 mg
  • Copper 0.67 mg
  • Copper 0.7 mg
  • Copper 0.70 mg
  • Copper 0.71 mg
  • Copper 0.75 mg
  • Copper 0.8 mg
  • Copper 0.9 mg
  • Copper 1 mcg
  • Copper 1 mg
  • Copper 1.0 mg
  • Copper 1.05 mg
  • Copper 1.1 mg
  • Copper 1.5 mcg
  • Copper 1.5 mg
  • Copper 1.77 mg
  • Copper 1.87 mg
  • Copper 10 mcg
  • Copper 100 mcg
  • Copper 10000 mcg
  • Copper 2 mg
  • Copper 2.2 mg
  • Copper 2.5 mg
  • Copper 20 mcg
  • Copper 20 mg
  • Copper 200 mg
  • Copper 220 mcg
  • Copper 25 mcg
  • Copper 250 mcg
  • Copper 250 mg
  • Copper 280 mcg
  • Copper 2mg
  • Copper 3 mg
  • Copper 3.0 mg
  • Copper 3.2 mg
  • Copper 3.92 mg
  • Copper 3.93 mg
  • Copper 300 mcg
  • Copper 3000 mcg
  • Copper 360 mcg
  • Copper 400 mcg
  • Copper 405 mcg
  • Copper 410 mcg
  • Copper 470 mcg
  • Copper 473 mcg
  • Copper 50 mcg
  • Copper 500 mcg
  • Copper 500 mg
  • Copper 630.5 mcg
  • Copper 75.65 mcg
  • Copper 750 mcg
  • Copper 8 mg
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    Copper Containing Brands

    Click on Prescription information to see Indications ( Uses ), Contraindications, Prescription information of respective Constituents.

    Brand Name Manufacturer Unit/Price Package unit/Price Constituents/Unit
    Capsule Beton Destin Laboratories Pvt. Ltd. 1 Capsule
    ₹ 0.56
    100 Capsul
    ₹ 56.00
  • More Information Vit B1 5 mg
  • More Information Vit B2 5 mg
  • More Information Vit B6 3 mg
  • More Information Calcium Pantothenate 10 mg
  • More Information Niacinamide 50 mg
  • More Information Vit A 5000 iu
  • More Information Iodine 0.1 mg
  • More Information Vit B12 15 mcg
  • More Information Selenium 70 mcg
  • More Information Vit E 10 iu
  • More Information Lycopene 2000 mcg
  • More Information Chromium (Chromic) 100 mcg
  • More Information Copper 1 mg
  • More Information Manganese 1 mg
  • More Information Zinc 20 mg
  • More Information Vit C 33.3 mg
  • See Brands having above combination
    Capsule Becadexamin Glaxo Smithkline Pharmaceuticals Ltd. 1 Capsule
    ₹ 0.80
    30 Capsule
    ₹ 24.00
  • More Information Vit B1 5 mg
  • More Information Vit B2 5 mg
  • More Information Vit C 75 mg
  • More Information Vit B12 5 mcg
  • More Information Vit A 5000 iu
  • More Information Folic Acid (Vit B9) 1 mg
  • More Information Vit B6 2 mg
  • More Information D-Panthenol 5 mg
  • More Information Vit D3 400 iu
  • More Information Nicotinamide 45 mg
  • More Information Zinc Sulphate 50 mg
  • More Information Copper Sulphate 0.1 mg
  • More Information Magnesium Oxide 0.15 mg
  • More Information Potassium Iodide 0.025 mg
  • More Information Ferrous Fumarate 50 mg
  • More Information Vit E 14 mg
  • More Information Calcium Dibasic Phosphate 70 mg
  • More Information Manganese Sulphate 0.01 mg
  • See Brands having above combination
    Syrup Bactivate (200 ml) BMW Pharmaco India Pvt Ltd 1 ml
    ₹ 0.33
    200 ml
    ₹ 66.00
  • More Information Vit A 2500 iu
  • More Information Cyanocobalamin 0.5 mcg
  • More Information Vit E 2.5 iu
  • More Information Zinc Sulphate 22.2 mg
  • More Information Potassium Iodide 50 mcg
  • More Information Copper Sulphate 100 mcg
  • More Information Cholecalciferol 100 iu
  • More Information D-Panthenol 1.25 mg
  • More Information Pyridoxine Hydrochloride IP 0.5 mg
  • More Information Nicotinamide 7.5 mg
  • More Information Thiamine Hydrochloride 0.75 mg
  • More Information Riboflavin 0.75 mg
  • More Information L-Lysine 5 mg
  • See Brands having above combination
    Tablet Cav M Ravian Life Sciences (P) Ltd 1 Tablet
    ₹ 0.48
    10 Tablet
    ₹ 4.80
  • More Information Calcium Carbonate 500 mg
  • More Information Zinc Sulphate 7.5 mg
  • More Information Copper Sulphate 1 mg
  • More Information Vit D3 250 iu
  • More Information Manganese Sulphate 1.8 mg
  • More Information Magnesium Hydroxide (Milk of Magnesia) 40 mg
  • See Brands having above combination
    Capsule Elvital SG Elnova Pharma 1 Capsule
    ₹ 0.70
    10 Capsule
    ₹ 7.00
  • More Information Vit B12 1 mcg
  • More Information Vit A 2500 iu
  • More Information Calcium Pantothenate 5 mg
  • More Information Folic Acid (Vit B9) 0.15 mg
  • More Information Calcium 75 mg
  • More Information Vit D3 200 iu
  • More Information Vit B1 1 mg
  • More Information Vit B2 1.5 mg
  • More Information Vit B6 1 mg
  • More Information Iodine 0.1 mg
  • More Information Magnesium 3 mg
  • More Information Phosphorus 58 mg
  • More Information Potassium 2 mg
  • More Information Vit E 5 mg
  • More Information Manganese 0.5 mg
  • More Information Zinc 10 mg
  • More Information Copper 0.5 mg
  • More Information Nicotinamide 5 mg
  • More Information Vit C 15 mg
  • More Information Gingseng Extract 42.5
  • More Information Iron Ferrous Fumarate 30 mg
  • See Brands having above combination
    Capsule Elnutra Elnova Pharma 1 Capsule
    ₹ 0.90
    10 Capsule
    ₹ 9.00
  • More Information Vit E 25 mg
  • More Information Vit A 10000 iu
  • More Information Zinc Oxide 7.5 mg
  • More Information Copper 1 mg
  • More Information Selenium 100 mcg
  • More Information L-Arginine 25 mg
  • More Information Manganese 1 mg
  • More Information Lycopene 10 mg
  • More Information Lutein 7 mg
  • See Brands having above combination
    Capsule Edinol Bayer India Ltd 1 Capsule
    ₹ 0.65
    20 Capsule
    ₹ 13.04
  • More Information Vit B6 3 mg
  • More Information Nicotinamide 50 mg
  • More Information Vit B2 10 mg
  • More Information Vit B1 10 mg
  • More Information Vit B12 5 mcg
  • More Information Folic Acid (Vit B9) 1 mg
  • More Information Vit C 150 mg
  • More Information Vit D3 1000 iu
  • More Information Vit A 10000 iu
  • More Information Dried Ferrous Sulphate 30 mg
  • More Information Vit E 15 mg
  • More Information Copper Sulphate 4 mg
  • More Information Di-Panthenol Alcohol 10 mg
  • More Information Vit K 1 mg
  • More Information Dried Yeast 50 mg
  • See Brands having above combination
    Syrup Hemblo (200 ml) Hinglaj Laboratories of India 1 ml
    ₹ 0.27
    200 ml
    ₹ 53.00
  • More Information Ferric Ammonium Citrate 200 mg
  • More Information Calcium Gluconate 150 mg
  • More Information Manganese Chloride 0.5 mg
  • More Information Copper Citrate 0.5 mg
  • See Brands having above combination
    Capsule Haemolar Plus Alar Laboratories Ltd 1 Capsule
    ₹ 0.30
    100 Capsul
    ₹ 30.00
  • More Information Folic Acid (Vit B9) 1.5 mg
  • More Information Vit C 75 mg
  • More Information Vit B12 5 mcg
  • More Information Vit B6 1.5 mg
  • More Information Elemental Zinc 10 mg
  • More Information Ferrous Fumarate 300 mg
  • More Information L-Lysine 40 mg
  • More Information Elemental Copper 0.1 mg
  • More Information Elemental Manganese 0.5 mg
  • More Information Succinic Acid 100 mg
  • See Brands having above combination
    Syrup Kidicare (100 ml) Meyer Organics Pvt Ltd. 1 ml
    ₹ 0.27
    100 ml
    ₹ 26.53
  • More Information Vit B2 1.5 mg
  • More Information Vit B6 1 mg
  • More Information Zinc 5 mg
  • More Information Vit D3 100 iu
  • More Information Vit B1 1.5 mg
  • More Information Vit A 1500 iu
  • More Information Magnesium 20 mg
  • More Information Vit B12 1.5 mcg
  • More Information L-Lysine 40 mg
  • More Information Vit E 3 mg
  • More Information Iron 7 mg
  • More Information Copper 0.3 mg
  • See Brands having above combination
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    Copper is used in following diseases

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    Drug - Drug Interactions of Copper
    Interaction
    Moderate, Consider therapy modification Intravenous copper vs Ascorbic Acid
    Moderate, Consider therapy modification Vitamin C (ascorbic acid) vs Copper