Vincristine vs Vaccines (Live)

Interacting Drugs
Vincristine
vs
Vaccines (Live)
Security Level
Major, Avoid combination
Mechanism
Vaccines (Live): Immunosuppressants may enhance the adverse/toxic effect of Vaccines (Live). Vaccinial infections may develop. Immunosuppressants may diminish the therapeutic effect of Vaccines (Live).
Management
Avoid use of live organism vaccines with immunosuppressants; live-attenuated vaccines should not be given for at least 3 months after immunosuppressants.

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