Vincristine vs Ritonavir

Interacting Drugs
Vincristine
vs
Ritonavir
Security Level
Moderate, Consider therapy modification
Mechanism
Ritonavir: May increase the serum concentration of VinCRIStine.
Management
Monitor closely for signs and symptoms of vincristine toxicity; consider temporary interruption of ritonavir antiviral therapy if patients develop significant toxicity with concurrent use.

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