Vinblastine vs Tolterodine

Interacting Drugs
Vinblastine
vs
Tolterodine
Security Level
Moderate, Consider therapy modification
Mechanism
Tolterodine: VinBLAStine may increase the serum concentration of Tolterodine.
Management
Reduce tolterodine dose to 1 mg twice daily (regular release formulation) or 2 mg daily (extended release formulation) (adult doses) and monitor for increased levels/effects of tolterodine with initiation of vinblastine therapy.

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