Vinblastine vs Lopinavir

Interacting Drugs
Vinblastine
vs
Lopinavir
Security Level
Moderate, Consider therapy modification
Mechanism
Lopinavir: May increase the serum concentration of VinBLAStine.
Management
Monitor closely for signs and symptoms of vinblastine toxicity; consider temporary interruption of lopinavir/ritonavir antiviral therapy if patients develop significant toxicity with concurrent use.

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