Ticagrelor vs Simvastatin

Interacting Drugs
Ticagrelor
vs
Simvastatin
Security Level
Moderate, Consider therapy modification
Mechanism
Simvastatin: Ticagrelor may increase the serum concentration of Simvastatin.
Management
Avoid using doses of simvastatin greater than 40 mg/day with ticagrelor. This specific recommendation is found in the U.S. prescribing information but not in the Canadian product monograph.

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Other Interactions of Simvastatin

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