Tadalafil vs Telaprevir

Interacting Drugs
Tadalafil
vs
Telaprevir
Security Level
Major, Avoid combination
Mechanism
Telaprevir: May increase the serum concentration of Tadalafil.
Management
Concurrent use of tadalafil for treatment of pulmonary arterial hypertension is contraindicated with telaprevir. Tadalafil for erectile dysfunction should be limited to 10 mg per 72 hours, with close monitoring for tadalafil toxicity.

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