Sildenafil vs Protease Inhibitors

Interacting Drugs
Sildenafil
vs
Protease Inhibitors
Security Level
Moderate, Consider therapy modification
Mechanism
Protease Inhibitors: May increase the serum concentration of Sildenafil.
Management
Erectile dysfunction: sildenafil max = 25 mg/48 hrs with ritonavir, atazanavir, or darunavir; starting dose = 25 mg with other protease inhibitors (adult doses). Contraindicated if sildenafil being used for pulmonary arterial hypertension.

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Other Interactions of Sildenafil

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Other Interactions of Protease Inhibitors

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