Promethazine, phenylephrine, and codeine vs Tricyclic Antidepressants

Interacting Drugs
Promethazine, phenylephrine, and codeine
vs
Tricyclic Antidepressants
Security Level
Moderate, Consider therapy modification
Mechanism
Tricyclic Antidepressants: May enhance the vasopressor effect of Alpha1-Agonists.
Management
Consider therapy modification

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