Promethazine, phenylephrine, and codeine vs FentaNYL

Interacting Drugs
Promethazine, phenylephrine, and codeine
vs
FentaNYL
Security Level
Minor, Monitor Therapy
Mechanism
FentaNYL: Alpha1-Agonists may decrease the serum concentration of FentaNYL. Specifically, fentanyl nasal spray serum concentrations may decrease and onset of effect may be delayed.
Management
Monitor therapy

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