Promethazine, phenylephrine, and codeine vs CYP2D6 Inhibitors (Strong)

Interacting Drugs
Promethazine, phenylephrine, and codeine
vs
CYP2D6 Inhibitors (Strong)
Security Level
Moderate, Consider therapy modification
Mechanism
CYP2D6 Inhibitors (Strong): May diminish the therapeutic effect of Codeine. These CYP2D6 inhibitors may prevent the metabolic conversion of codeine to its active metabolite morphine.
Management
Consider therapy modification

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Other Interactions of Promethazine, phenylephrine, and codeine

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Other Interactions of CYP2D6 Inhibitors (Strong)

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