Pregabalin vs Mefloquine

Interacting Drugs
Pregabalin
vs
Mefloquine
Security Level
Moderate, Consider therapy modification
Mechanism
Mefloquine: May diminish the therapeutic effect of Anticonvulsants. Mefloquine may decrease the serum concentration of Anticonvulsants.
Management
Mefloquine is contraindicated for malaria prophylaxis in persons with a history of convulsions. Monitor anticonvulsant concentrations and treatment response closely with concurrent use.

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