Ofloxacin (systemic) vs Quinapril

Interacting Drugs
Ofloxacin (systemic)
vs
Quinapril
Security Level
Moderate, Consider therapy modification
Mechanism
Quinapril: May decrease the serum concentration of Quinolone Antibiotics.
Management
Separate doses of quinapril and oral quinolones by at least 2 hours in order to reduce the risk of interaction. Monitor for reduced efficacy of the quinolone if these products are used concomitantly.

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