Magnesium carbonate, calcium carbonate, and folic acid vs ACE Inhibitors

Interacting Drugs
Magnesium carbonate, calcium carbonate, and folic acid
vs
ACE Inhibitors
Security Level
Moderate, Consider therapy modification
Mechanism
ACE Inhibitors: Antacids may decrease the serum concentration of ACE Inhibitors.
Management
Separate fosinopril administration from antacids by at least 2 hours. US and Canadian recommendations for use of other ACE- inhibitors with antacids may vary. Consult appropriate labeling. Monitor for decreased therapeutic effects of ACE-inhibitors. Exceptions: Ramipril.

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