Lovastatin vs CycloSPORINE

Interacting Drugs
Lovastatin
vs
CycloSPORINE
Security Level
Moderate, Consider therapy modification
Mechanism
CycloSPORINE: May increase the serum concentration of HMG-CoA Reductase Inhibitors.
Management
Use of cyclosporine with simvastain or pitavastatin is contraindicated. U.S. and Canadian recommendations for some statins may differ, see appropriate prescribing information. Monitor closely for myotoxicity with concurrent use.

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