Lansoprazole, amoxicillin, and clarithromycin vs Nelfinavir

Interacting Drugs
Lansoprazole, amoxicillin, and clarithromycin
vs
Nelfinavir
Security Level
Major, Avoid combination
Mechanism
Nelfinavir: Proton Pump Inhibitors may decrease serum concentrations of the active metabolite(s) of Nelfinavir. Proton Pump Inhibitors may decrease the serum concentration of Nelfinavir.
Management
Avoid combination

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