Lansoprazole, amoxicillin, and clarithromycin vs MethylPREDNISolone

Interacting Drugs
Lansoprazole, amoxicillin, and clarithromycin
vs
MethylPREDNISolone
Security Level
Moderate, Consider therapy modification
Mechanism
MethylPREDNISolone: CYP3A4 Inhibitors (Strong) may increase the serum concentration of MethylPREDNISolone.
Management
Consider methylprednisolone dose titration and/or adjustments in patients receiving strong CYP3A4 inhibitors (eg, azole antifungals, protease inhibitors) and monitor for increased steroid related adverse effects.

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