Lansoprazole, amoxicillin, and clarithromycin vs Clopidogrel

Interacting Drugs
Lansoprazole, amoxicillin, and clarithromycin
vs
Clopidogrel
Security Level
Minor, Monitor Therapy
Mechanism
Clopidogrel: Macrolide Antibiotics may diminish the therapeutic effect of Clopidogrel.
Management
Monitor therapy

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Post Review about Lansoprazole, amoxicillin, and clarithromycin vs Clopidogrel

Lansoprazole, amoxicillin, and clarithromycin vs Clopidogrel

Interacting Drugs
Lansoprazole, amoxicillin, and clarithromycin
vs
Clopidogrel
Security Level
Moderate, Consider therapy modification
Mechanism
Clopidogrel: Lansoprazole may decrease serum concentrations of the active metabolite(s) of Clopidogrel.
Management
Due to the possible risk for impaired clopidogrel effectiveness, clinicians should carefully consider the need for proton pump inhibitor therapy in patients receiving clopidogrel. Other acid-lowering therapies do not appear to share this interaction.

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Post Review about Lansoprazole, amoxicillin, and clarithromycin vs Clopidogrel