Imipenem and cilastatin vs CycloSPORINE (Systemic)

Interacting Drugs
Imipenem and cilastatin
vs
CycloSPORINE (Systemic)
Security Level
Minor, Monitor Therapy
Mechanism
CycloSPORINE (Systemic): May enhance the neurotoxic effect of Imipenem. Imipenem may decrease the serum concentration of CycloSPORINE (Systemic). Imipenem may increase the serum concentration of CycloSPORINE (Systemic).
Management
Monitor therapy

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