Glyburide and metformin vs Bosentan

Interacting Drugs
Glyburide and metformin
vs
Bosentan
Security Level
Major, Avoid combination
Mechanism
Bosentan: GlyBURIDE may enhance the hepatotoxic effect of Bosentan. GlyBURIDE may increase the metabolism of Bosentan. Bosentan may increase the metabolism of GlyBURIDE.
Management
Avoid combination

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Other Interactions of Bosentan

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