Famotidine, calcium carbonate, and magnesium hydroxide vs Posaconazole

Interacting Drugs
Famotidine, calcium carbonate, and magnesium hydroxide
vs
Posaconazole
Security Level
Moderate, Consider therapy modification
Mechanism
Posaconazole: H2-Antagonists may decrease the serum concentration of Posaconazole.
Management
Avoid concurrent use whenever possible. Monitor patients closely for decreased antifungal effects if this combination is used. Consider using a noninteracting antifungal as appropriate.

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