Estradiol and norethindrone vs LamoTRIgine

Interacting Drugs
Estradiol and norethindrone
vs
LamoTRIgine
Security Level
Moderate, Consider therapy modification
Mechanism
LamoTRIgine: May decrease the serum concentration of Contraceptives (Progestins).
Management
Women using progestin-only “minipill” products may be at risk for contraceptive failure; it is unclear if other progestin-containing products would be significantly impacted. Alternative, non-hormonal, means of contraception are recommended.

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