Estradiol and norethindrone vs Fosphenytoin

Interacting Drugs
Estradiol and norethindrone
vs
Fosphenytoin
Security Level
Moderate, Consider therapy modification
Mechanism
Fosphenytoin: May diminish the therapeutic effect of Contraceptives (Progestins). Contraceptive failure is possible.
Management
Contraceptive failure is possible. Use of an alternative, nonhormonal contraceptive is recommended.

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