Estradiol and norethindrone vs Barbiturates

Interacting Drugs
Estradiol and norethindrone
vs
Barbiturates
Security Level
Moderate, Consider therapy modification
Mechanism
Barbiturates: May diminish the therapeutic effect of Contraceptives (Progestins). Contraceptive failure is possible.
Management
Use of alternative, nonhormonal contraceptives is recommended.

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