Drospirenone and estradiol vs Boceprevir

Interacting Drugs
Drospirenone and estradiol
vs
Boceprevir
Security Level
Moderate, Consider therapy modification
Mechanism
Boceprevir: May increase the serum concentration of Contraceptives (Progestins).
Management
Do not rely on systemic hormonal contraceptives for contraception during treatment with boceprevir. Patients receiving combination regimens containing ribavirin should use two alternative effective means of contraception.

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Drospirenone and estradiol vs Boceprevir

Interacting Drugs
Drospirenone and estradiol
vs
Boceprevir
Security Level
Major, Avoid combination
Mechanism
Boceprevir: May increase the serum concentration of Drospirenone.
Management
Avoid combination

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