Digoxin vs Spironolactone

Interacting Drugs
Digoxin
vs
Spironolactone
Security Level
Minor, Monitor Therapy
Mechanism
Spironolactone: May increase the serum concentration of Digoxin. Spironolactone (and/or its metabolites) may also interfere with the assays used to determine Digoxin concentrations, falsely increasing or decreasing Digoxin concentrations.
Management
Monitor therapy

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Other Interactions of Spironolactone

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