Didanosine vs Lopinavir

Interacting Drugs
Didanosine
vs
Lopinavir
Security Level
Moderate, Consider therapy modification
Mechanism
Lopinavir: May decrease the serum concentration of Didanosine. This interaction refers only to lopinavir/ritonavir oral solution, which must be taken with food, and is principally the result of a food-didanosine interaction.
Management
Didanosine should be administered 1 hour prior to or 2 hours after administration of lopinavir/ritonavir oral solution (which must be taken with food). Didanosine and lopinavir/ritonavir tablets can be administered together.

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