Diclofenac and misoprostol vs Nonsteroidal Anti-Inflammatory Agents

Interacting Drugs
Diclofenac and misoprostol
vs
Nonsteroidal Anti-Inflammatory Agents
Security Level
Minor, Monitor Therapy
Mechanism
Nonsteroidal Anti-Inflammatory Agents: May enhance the adverse/toxic effect of Antiplatelet Agents. An increased risk of bleeding may occur. Nonsteroidal Anti-Inflammatory Agents may diminish the cardioprotective effect of Antiplatelet Agents. This interaction is likely specific to aspirin, and not to other antiplatelet agents.
Management
Monitor therapy

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