Diclofenac and misoprostol vs Bisphosphonate Derivatives

Interacting Drugs
Diclofenac and misoprostol
vs
Bisphosphonate Derivatives
Security Level
Minor, Monitor Therapy
Mechanism
Bisphosphonate Derivatives: Nonsteroidal Anti-Inflammatory Agents may enhance the adverse/toxic effect of Bisphosphonate Derivatives. Both an increased risk of gastrointestinal ulceration and an increased risk of nephrotoxicity are of concern.
Management
Monitor therapy

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