Darunavir vs Sildenafil

Interacting Drugs	Darunavir vs Sildenafil
Security Level
Mechanism	Sildenafil: CYP3A4 Inhibitors (Strong) may increase the serum concentration of Sildenafil.
Management	When used for treatment of pulmonary arterial hypertension, use of sildenafil with strong CYP3A4 inhibitors should be avoided. When used for erectile dysfunction, starting dose should be reduced to 25 mg. Max dose with ritonavir is 25 mg per 48 hours.

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Other Interactions of Darunavir

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Other Interactions of Sildenafil

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Interacting Drugs	Darunavir vs Sildenafil
Security Level
Mechanism	Sildenafil: Protease Inhibitors may increase the serum concentration of Sildenafil.
Management	Erectile dysfunction: sildenafil max = 25 mg/48 hrs with ritonavir, atazanavir, or darunavir; starting dose = 25 mg with other protease inhibitors (adult doses). Contraindicated if sildenafil being used for pulmonary arterial hypertension.

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Other Interactions of Darunavir

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Other Interactions of Sildenafil

We are Developing Our database, More results coming soon.