Clarithromycin vs Corticosteroids (Orally Inhaled)

Interacting Drugs
Clarithromycin
vs
Corticosteroids (Orally Inhaled)
Security Level
Minor, Monitor Therapy
Mechanism
Corticosteroids (Orally Inhaled): CYP3A4 Inhibitors (Strong) may increase the serum concentration of Corticosteroids (Orally Inhaled).
Management
Monitor for signs and symptoms of adrenal suppression if inhaled budesonide or mometasone are coadministered with a strong CYP3A4 inhibitor. Avoid combining inhaled fluticasone with any strong CYP3A4 inhibitor. Exceptions: Beclomethasone; Beclomethasone (Oral Inhalation); Triamcinolone; Triamcinolone (Systemic).

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