Chlorthalidone vs Allopurinol

Interacting Drugs
Chlorthalidone
vs
Allopurinol
Security Level
Minor, Monitor Therapy
Mechanism
Allopurinol: Thiazide Diuretics may enhance the potential for allergic or hypersensitivity reactions to Allopurinol. Thiazide Diuretics may increase the serum concentration of Allopurinol. Specifically, Thiazide Diuretics may increase the concentration of Oxypurinol, an active metabolite of Allopurinol.
Management
Monitor therapy

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