Captopril and hydrochlorothiazide vs Sodium Phosphates

Interacting Drugs
Captopril and hydrochlorothiazide
vs
Sodium Phosphates
Security Level
Moderate, Consider therapy modification
Mechanism
Sodium Phosphates: Diuretics may enhance the nephrotoxic effect of Sodium Phosphates. Specifically, the risk of acute phosphate nephropathy may be enhanced.
Management
Consider avoiding this combination by temporarily suspending treatment with diuretics, or seeking alternatives to oral sodium phosphate bowel preparation. If the combination cannot be avoided, hydrate adequately and monitor fluid and renal status.

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Post Review about Captopril and hydrochlorothiazide vs Sodium Phosphates

Captopril and hydrochlorothiazide vs Sodium Phosphates

Interacting Drugs
Captopril and hydrochlorothiazide
vs
Sodium Phosphates
Security Level
Moderate, Consider therapy modification
Mechanism
Sodium Phosphates: ACE Inhibitors may enhance the nephrotoxic effect of Sodium Phosphates. Specifically, the risk of acute phosphate nephropathy may be enhanced.
Management
Consider avoiding this combination by temporarily suspending treatment with ACEIs, or seeking alternatives to oral sodium phosphate bowel preparation. If the combination cannot be avoided, maintain adequate hydration and monitor renal function closely.

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Post Review about Captopril and hydrochlorothiazide vs Sodium Phosphates