Calcium polystyrene sulfonate vs Thyroid Products

Interacting Drugs
Calcium polystyrene sulfonate
vs
Thyroid Products
Security Level
Moderate, Consider therapy modification
Mechanism
Thyroid Products: Calcium Polystyrene Sulfonate may decrease the serum concentration of Thyroid Products.
Management
To minimize risk of interaction, separate dosing of oral calcium polystyrene sulfonate and thyroid products (eg, levothyroxine) or administer calcium polystyrene sulfonate rectally. Monitor for signs/symptoms of hypothyroidism with concomitant use (oral).

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