Calcium carbonate and simethicone vs Cefditoren

Interacting Drugs
Calcium carbonate and simethicone
vs
Cefditoren
Security Level
Moderate, Consider therapy modification
Mechanism
Cefditoren: Antacids may decrease the serum concentration of Cefditoren.
Management
Concomitant use of cefditoren with antacids is not recommended. Consider alternative methods to control acid reflux (eg, diet modification) or alternative antimicrobial therapy. If antacid therapy can not be avoided, separate dosing by several hours.

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